SS-31

SS-31 (elamipretide, also designated MTP-131) is a synthetic, cell-permeable tetrapeptide with an alternating aromatic–cationic structure (D-Arg-2′,6′-dimethyltyrosine-Lys-Phe-NH₂). It belongs to the Szeto-Schiller family of mitochondria-targeted peptides and is one of the most extensively characterised compounds in mitochondrial medicine.

Mechanism

SS-31 concentrates selectively in the inner mitochondrial membrane, where it binds cardiolipin — the signature phospholipid that organises the membrane's cristae architecture and anchors the electron transport chain. By stabilising cardiolipin, SS-31 restores proper cristae curvature, improves the coupling efficiency of oxidative phosphorylation, and reduces the electron leakage that generates reactive oxygen species. Importantly, it is not an antioxidant that scavenges free radicals after the fact; it addresses the structural cause of their overproduction.

What the studies show

• Increased ATP output and improved respiratory efficiency in energy-demanding tissue
• Substantial reduction in mitochondrial reactive oxygen species and oxidative damage markers
• Restoration of muscle function and fatigue resistance in models of age-related mitochondrial decline
• Preservation of cardiac and renal tissue in ischaemia-reperfusion injury models
• Protection of cristae structure in models of primary mitochondrial myopathy

Because mitochondrial efficiency underlies endurance, recovery and cellular longevity, SS-31 has become a reference compound in bioenergetics.

Frequently asked questions

How much does SS-31 cost in Egypt?
Prices for the single vial and the 4-vial kit are shown in Egyptian pounds on this page and kept up to date, so there is no need to message for a quote.

Are SS-31 and elamipretide the same?
Yes. SS-31, elamipretide and MTP-131 are three names for the same mitochondria-targeted tetrapeptide.

How long does delivery take in Egypt?
Orders typically arrive within 3 to 5 days, delivered to every governorate, in insulated packaging with cold packs.

How do I know the vial is genuine?
Every vial arrives factory-sealed in the manufacturer’s original packaging with the lot number intact. On a first order we can send you the batch serial and the quality certificate to verify against the manufacturer.

Often used alongside MOTS-c and NAD+, or browse the full longevity range in Egypt.